ICG酰肼
英文名称：ICG hydrazide
产品参数
| Ex (nm) | 789 | Em (nm) | 813 |
| 分子量 | 973.04 | 溶剂 | DMSO |
| 存储条件 | 在零下15度以下保存, 避免光照 |
产品概述
产品货期
咨询
适用范围
用于标记肽、蛋白和核酸
产品介绍
AAT Bioquest生产的吲哚菁绿ICG 酰肼标记醛基、酮基。这种染料也被称为Cardio Green。非侵入性近红外（NIR）荧光成像染料ICG经FDA批准用于眼科血管造影，以确定心输出量和肝血流量和功能。由于红外频率穿透视网膜层，允许ICG血管造影成像比荧光血管造影更深的循环模式。ICG与血浆蛋白紧密结合，并限制在血管系统中。ICG的半衰期为150至180秒，仅通过肝脏从胆汁液中排出。研究表明ICG在注射后20分钟内靶向动脉粥样硬化，并提供足够的信号增强，用于体内检测动脉粥样硬化兔中富含脂质，发炎，冠状动脉大小的斑块。离体荧光反射成像显示，与注射生理盐水的动脉粥样硬化兔相比，注射ICG的动脉粥样硬化兔的斑块靶 - 背景比高。它还用于其他医学诊断和癌症患者，用于检测实体瘤，淋巴结的定位，以及重建手术期间的血管造影，视网膜和脉络膜血管的可视化以及光动力疗法。在癌症诊断和治疗中，ICG可以用作成像染料和高温剂。在可见光范围内吸收很少是自发荧光低的原因，组织吸光度和NIR波长（700-900nm）的散射。
试剂应用文献
Biological studies of an ICG-tagged aptamer as drug delivery system for malignant melanoma
Authors: Lopes-Nunes, J{\'e}ssica and Lifante, Jos{\'e} and Shen, Yingli and Ximendes, Erving C and Jaque, Daniel and Iglesias-de la Cruz, M Carmen and Cruz, Carla
Journal: European Journal of Pharmaceutics and Biopharmaceutics (2020): 228--235
Authors: Lopes-Nunes, J{\'e}ssica and Lifante, Jos{\'e} and Shen, Yingli and Ximendes, Erving C and Jaque, Daniel and Iglesias-de la Cruz, M Carmen and Cruz, Carla
Journal: European Journal of Pharmaceutics and Biopharmaceutics (2020): 228--235
Assessment of Lexiscan for Blood Brain Barrier disruption to facilitate Fluorescence brain imaging
Authors: Pak, Rebecca W and Le, Hanh and Valentine, Heather and Thorek, Daniel and Rahmim, Arman and Wong, Dean and Kang, Jin U
Journal: (2017): ATu3B--2
Authors: Pak, Rebecca W and Le, Hanh and Valentine, Heather and Thorek, Daniel and Rahmim, Arman and Wong, Dean and Kang, Jin U
Journal: (2017): ATu3B--2
Bioengineering of injectable encapsulated aggregates of pluripotent stem cells for therapy of myocardial infarction
Authors: Zhao, Shuting and Xu, Zhaobin and Wang, Hai and Reese, Benjamin E and Gushchina, Liubov V and Jiang, Meng and Agarwal, Pranay and Xu, Jiangsheng and Zhang, Mingjun and Shen, Rulong and others, undefined
Journal: Nature Communications (2016): 13306
Authors: Zhao, Shuting and Xu, Zhaobin and Wang, Hai and Reese, Benjamin E and Gushchina, Liubov V and Jiang, Meng and Agarwal, Pranay and Xu, Jiangsheng and Zhang, Mingjun and Shen, Rulong and others, undefined
Journal: Nature Communications (2016): 13306
Single-Layer MoS2 Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors
Authors: Chen, Jingqin and Liu, Chengbo and Hu, Dehong and Wang, Feng and Wu, Haiwei and Gong, Xiaojing and Liu, Xin and Song, Liang and Sheng, Zonghai and Zheng, Hairong
Journal: Advanced Functional Materials (2016)
Authors: Chen, Jingqin and Liu, Chengbo and Hu, Dehong and Wang, Feng and Wu, Haiwei and Gong, Xiaojing and Liu, Xin and Song, Liang and Sheng, Zonghai and Zheng, Hairong
Journal: Advanced Functional Materials (2016)
Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High-Efficiency Upconversion Nanocomposites
Authors: Liu, Yu and Kang, Ning and Lv, Jing and Zhou, Zijian and Zhao, Qingliang and Ma, Lingceng and Chen, Zhong and Ren, Lei and Nie, Liming
Journal: Advanced Materials (2016)
Authors: Liu, Yu and Kang, Ning and Lv, Jing and Zhou, Zijian and Zhao, Qingliang and Ma, Lingceng and Chen, Zhong and Ren, Lei and Nie, Liming
Journal: Advanced Materials (2016)
