刀豆蛋白A(ConA),AF488标记

XFD488 由 AAT Bioquest 生产，具有与 Alexa Fluor® 488 相同的化学结构（Alexa Fluor® 是 ThermoFisher 的商标）。刀豆球蛋白 A (ConA) 是一种凝集素，它与各种糖、糖蛋白和糖脂中的某些结构特异结合。Con A是一种T细胞有丝分裂原，它能免疫系统，募集淋巴细胞并诱导细胞因子的产生。除了有丝分裂活性外，ConA还可以通过线粒体介导的细胞凋亡和自噬诱导细胞程序性死亡。ConA还被报道NFAT（活化T细胞的核因子），NFAT是一个转录因子家族，在免疫系统的发育和功能中起重要作用，包括T细胞受体（TCR）的参与。ConA广泛应用于生物学和生物化学中，用来表征细胞表面的糖蛋白和其他含糖物质。还可用于凝集素亲和层析纯化糖基化大分子，以及研究各种免疫细胞的免疫调节作用。ConA在B-聚糖分支结构的末端位置特异性地结合α-D-甘露糖基和α-D-葡萄糖基残基（仅在碳2上的醇中不同的两个己糖）。刀豆球蛋白 A (Con A) 是细胞生物学中应用广泛的凝集素之一。XFD488 -刀豆蛋白A(ConA)缀合物选择性地结合到A-甘露吡喃糖基和A-葡萄糖吡喃糖基残基上，发出明亮的红色荧光。百萤生物是AAT Bioquest的中国代理商，为您提供优质的XFD488-刀豆蛋白A(ConA)缀合物。 

 

Short-term high-fat diet intake leads to exacerbation of concanavalin A-induced liver injury through the induction of procoagulation state.
Authors: Nanizawa, Eri and Tamaki, Yuki and Sono, Reika and Miyashita, Rintaro and Hayashi, Yumi and Kanbe, Ayumu and Ito, Hiroyasu and Ishikawa, Tetsuya
Journal: Biochemistry and biophysics reports (2020): 100736

 

Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Authors: Zhang, Peng and Yin, Yuping and Wang, Tao and Li, Wei and Li, Chengguo and Zeng, Xiangyu and Yang, Wenchang and Zhang, Ruizhi and Tang, Yu and Shi, Liang and Li, Ruidong and Tao, Kaixiong
Journal: Free radical biology & medicine (2020): 23-36

 

Membrane-associated gamma-glutamyl transferase and alkaline phosphatase in the context of concanavalin A- and wheat germ agglutinin-reactive glycans mark seminal prostasome populations from normozoospermic and oligozoospermic men.
Authors: Janković, Tamara and Goč, Sanja and Mitić, Ninoslav and Danilović Luković, Jelena and Janković, Miroslava
Journal: Upsala journal of medical sciences (2020): 10-18

 

Antioxidant Capacity and Hepatoprotective Role of Chitosan-Stabilized Selenium Nanoparticles in Concanavalin A-Induced Liver Injury in Mice.
Authors: Bai, Kaikai and Hong, Bihong and He, Jianlin and Huang, Wenwen
Journal: Nutrients (2020)

 

The farnesyltransferase inhibitor tipifarnib protects against autoimmune hepatitis induced by Concanavalin A.
Authors: Guo, Jie and Shirozu, Kazuhiro and Akahoshi, Tomohiko and Mizuta, Yukie and Murata, Masaharu and Yamaura, Ken
Journal: International immunopharmacology (2020): 106462

 

Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy.
Authors: Cantelli, Andrea and Piro, Francesca and Pecchini, Pietro and Di Giosia, Matteo and Danielli, Alberto and Calvaresi, Matteo
Journal: Journal of photochemistry and photobiology. B, Biology (2020): 111852

 

Developmental exposure to low doses of dichlorodiphenyltrichloroethane impairs proliferative response of thymic lymphocytes to Concanavalin A in rats.
Authors: Yaglova, Nataliya V and Tsomartova, Elina S and Obernikhin, Sergey S and Ivanova, Marina Y and Chereshneva, Elizaveta V and Muhamedova, Svetlana G and Lomanovskaya, Tatiana A and Yaglov, Valentin V
Journal: Heliyon (2020): e03608

 

Concanavalin A Toxicity Towards Potato Psyllid and Apoptosis Induction in Midgut Cells.
Authors: Tang, Xiao-Tian and Ibanez, Freddy and Tamborindeguy, Cecilia
Journal: Insects (2020)

 

Concanavalin A Enhanced Proliferation and Osteogenic Differentiation of Dental Pulp Stem Cells.
Authors: Suardita, Ketut and Arundina, Ira and Tedjosasongko, Udijanto and Yuliati, Anita and Peeters, Harry Huiz and Wijaksana, I Komang Evan and Surboyo, Meircurius Dwi Condro
Journal: European journal of dentistry (2020): 123-127

 

Mycophenolate mofetil attenuates concanavalin A-induced acute liver injury through modulation of TLR4/NF-κB and Nrf2/HO-1 pathways.
Authors: Serrya, Marwa S and Zaghloul, Marwa S
Journal: Pharmacological reports : PR (2020)