BG琥珀酰亚胺酯

产品基本信息

产品名称：BG琥珀酰亚胺酯

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

外观：固体

溶剂：DMSO

产品介绍

SNAP蛋白质标记系统使几乎任何分子都可以特异性地，共价地结合到目标蛋白质上。SNAP标签是基于人O6-烷基鸟嘌呤-DNA-烷基转移酶（hAGT）的蛋白质。SNAP标签的底物是荧光团，生物素或通过苄基接头与鸟嘌呤或氯嘧啶去掉基团缀合的微珠。在标记反应中，底物取代的苄基共价附着于SNAP标签。BG琥珀酰亚胺酯是一种可与胺反应的结构单元，可从含胺的标记物或生物靶标制备SNAP底物。BG琥珀酰亚胺酯构建基块为各种SNAP标签底物的开发提供了便利，这些底物用于标记SNAP标签融合蛋白，可用于多种生物学应用。

参考文献

Photo-SNAP-tag, a Light-Regulated Chemical Labeling System.
Authors: Cleveland, Joseph D and Tucker, Chandra L
Journal: ACS chemical biology (2020)

The covalent SNAP tag for protein display quantification and low-pH protein engineering.
Authors: Jin, Wei and Madan, Bharat and Mussman, Brooklyn K and Hailemariam, Amen T and Fahad, Ahmed S and Wolfe, Jacy R and Kwon, Young Do and Zhang, Baoshan and Shapiro, Lawrence and Kwong, Peter D and DeKosky, Brandon J
Journal: Journal of biotechnology (2020): 50-56

Visualizing and Manipulating Biological Processes by Using HaloTag and SNAP-Tag Technologies.
Authors: Hoelzel, Conner A and Zhang, Xin
Journal: Chembiochem : a European journal of chemical biology (2020): 1935-1946

A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede.
Authors: Jung, Kwan Ho and Fares, Matthew and Grainger, Leeann S and Wolstenholme, Charles H and Hou, Anna and Liu, Yu and Zhang, Xin
Journal: Organic & biomolecular chemistry (2019): 1906-1915

Applications of SNAP-tag technology in skin cancer therapy.
Authors: Padayachee, Eden Rebecca and Adeola, Henry Ademola and Van Wyk, Jennifer Catherine and Nsole Biteghe, Fleury Augustine and Chetty, Shivan and Khumalo, Nonhlanhla Patience and Barth, Stefan
Journal: Health science reports (2019): e103

One-step site-specific antibody fragment auto-conjugation using SNAP-tag technology.
Authors: Hussain, Ahmad Fawzi and Heppenstall, Paul A and Kampmeier, Florian and Meinhold-Heerlein, Ivo and Barth, Stefan
Journal: Nature protocols (2019): 3101-3125

[Combined application of SNAP-tag and fluorescence technique in in-situ protein analysis].
Authors: Qiao, Qinglong and Zhou, Wei and Chen, Jie and Liu, Wenjuan and Miao, Lu and Yin, Wenting and Xu, Zhaochao
Journal: Se pu = Chinese journal of chromatography (2019): 872-877

Beyond O6-Benzylguanine: O6-(5-Pyridylmethyl)guanine as a Substrate for the Self-Labeling Enzyme SNAP-Tag.
Authors: Macias-Contreras, Miguel and He, Huan and Zhu, Lei
Journal: Bioconjugate chemistry (2018): 4104-4109

Imaging Newly Synthesized and Old Histone Variant Dynamics Dependent on Chaperones Using the SNAP-Tag System.
Authors: Torné, Júlia and Orsi, Guillermo A and Ray-Gallet, Dominique and Almouzni, Geneviève
Journal: Methods in molecular biology (Clifton, N.J.) (2018): 207-221

A wash-free SNAP-tag fluorogenic probe based on the additive effects of quencher release and environmental sensitivity.
Authors: Leng, Shuang and Qiao, Qinglong and Miao, Lu and Deng, Wuguo and Cui, Jingnan and Xu, Zhaochao
Journal: Chemical communications (Cambridge, England) (2017): 6448-6451