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氨基修饰剂 C6 dT

英文名称:Amino-Modifier C6 dT
氨基修饰剂 C6 dT
价格 1882
产品规格
100 umoles

产品货号
产品参数
Ex (nm)-Em (nm)-
分子量995.05溶剂MeCN
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:氨基修饰剂 C6 dT

储存条件:-15℃避光防潮

保质期:6个月

 

产品物理化学光谱特性

分子量:995.05

外观:固体

溶剂:MeCN

 

产品介绍

氨基修饰剂 C6 dT 是一种方便的亚磷酰胺试剂,用于在寡核苷酸合成中从 dT 引入氨基。在正常的寡核苷酸合成过程中添加氨基修饰剂 C6 dT。 TFA 保护基团在标准氢氧化铵脱保护过程中被去除。序列修饰符设计用于自动合成。氨基修饰的 dT 可以通过标准肽偶联或通过中间体 N-羟基琥珀酰亚胺 (NHS) 酯直接偶联到分子上。在寡核苷酸合成过程中,可以添加氨基修饰剂 dT 代替 dT 残基。 C6 类似物上的伯胺通过具有总共 7 个 -10 个原子的间隔臂与寡核苷酸分离,并且可以标记或连接到可检测标签上,例如荧光染料或酶。百萤生物是AAT Bioquest的中国代理商,为您提供优质的氨基修饰剂 C6 dT。 

 

参考文献

FRET-based dual-labeled oligonucleotide probes detect target DNA by probing a minor groove environment.
Authors: Koboku, Shoutoku and Tsukada, Takumi and Oku, Yurino and Kobayashi, Saika and Saito, Yoshio
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High throughput purification of amino-modified oligonucleotides and its application to novel detection system of gene expression.
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