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7-羟基-4-三氟甲基香豆素 CAS 575-03-1

英文名称:Beta-trifluoromethylumbelliferone [7-Hydroxy-4-trifluoromethylcoumarin] *CAS 575-03-1*
产品参数
Ex (nm)385Em (nm)499
分子量230.14溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:7-羟基-4-三氟甲基香豆素 

CAS:575-03-1

储存条件:-15℃避光防潮

保质期:36个月

 

产品物理化学光谱特性

分子量:230.14

溶剂:DMSO

激发波长(nm):385

发射波长(nm):502

 

产品介绍

7-羟基-4-三氟甲基香豆素是美国AAT Bioquest生产的香豆素类染料,这种复合物被用作以7-羟基-4-三氟甲基香豆素为基础的酶底物校准标准液,它是pH依赖性荧光。百萤生物是AAT Bioquest的中国代理商,为您提供优质的7-羟基-4-三氟甲基香豆素。 

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溶解方案(溶剂以说明书为准)

  0.1 mg 0.5 mg 1 mg 5 mg 10 mg
1 mM 434.518 µL 2.173 mL 4.345 mL 21.726 mL 43.452 mL
5 mM 86.904 µL 434.518 µL 869.036 µL 4.345 mL 8.69 mL
10 mM 43.452 µL 217.259 µL 434.518 µL 2.173 mL 4.345 mL

 

参考文献

Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes
Authors: Chang TK, Crespi CL, Waxman DJ.
Journal: Methods Mol Biol (2006): 97

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil)
Authors: Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S.
Journal: Drug Metab Dispos (2004): 267

Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver
Authors: Dean B, Arison B, Chang S, Thomas PE, King C.
Journal: Arch Biochem Biophys (2004): 55

Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases
Authors: Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
Journal: Drug Metab Dispos (2004): 587

Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10
Authors: Jinno H, Saeki M, Tanaka-Kagawa T, Hanioka N, Saito Y, Ozawa S, Ando M, Shirao K, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J.
Journal: Drug Metab Dispos (2003): 528

Generation and validation of rapid computational filters for cyp2d6 and cyp3a4
Authors: Ekins S, Berbaum J, Harrison RK.
Journal: Drug Metab Dispos (2003): 1077

Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity
Authors: Huynh HT, Teel RW.
Journal: Anticancer Res (2002): 1699

Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes
Authors: Renwick AB, Lavignette G, Worboy PD, Williams B, Surry D, Lewis DF, Price RJ, Lake BG, Evans DC.
Journal: Xenobiotica (2001): 861

Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4
Authors: Renwick AB, Lewis DF, Fulford S, Surry D, Williams B, Worboys PD, Cai X, Wang RW, Price RJ, Lake BG, Evans DC.
Journal: Xenobiotica (2001): 187

CYP isoform induction screening in 96-well plates: use of 7-benzyloxy-4-trifluoromethylcoumarin as a substrate for studies with rat hepatocytes
Authors: Price RJ, Surry D, Renwick AB, Meneses-Lorente G, Lake BG, Evans DC.
Journal: Xenobiotica (2000): 781